British Transport Police, London Fire Brigade and London Ambulance Service are now at the scene.
Emergency services arrived at the station just after 7pm following reports of a small explosion.
"Inquiries are ongoing to establish the cause of the reported explosion, which appears to have been minor".
"We are not aware of any serious injury", the statement added.
Local reports suggest that one person was taken out of the station on a stretcher.
Witnesses described smelling "burning rubber" and seeing "six-foot flames" at the entrance to Southgate underground station in Enfield.
Haluk Ozkan was about to get on a bus outside the station when he smelt something burning.
"The police moved us on, but they said there was an explosion in the station", he said.
Police officers are seen after a minor explosion was reported at Southgate underground station, London, Britain June 19 2018, in this picture obtained from social media.
Darren Yarlett, 36, was driving home in Southgate but police had cordoned off roads near the station. However, BTP later tweeted: "Enquiries continue but we do not believe this to be terror related at [this] time".
"The scene has been examined by specialist officers".