While speaking to People on Tuesday, Aretha's nephew Tim Franklin told the publication that the family is hopeful she will be able to pull through, despite accounts that the singer has been ill for a long time and that "death is imminent".
Aretha's publicist Gwendolyn Quinn told Associated Press that the 76-year-old has been visited by family and friends including Stevie Wonder, her ex-husband, actor Glynn Turman and United States activist Reverend Jesse Jackson.
At her concert in Detroit on Monday night with Jay-Z, Beyonce thanked Franklin for her "beautiful music" and said "we love you".
He joined a chorus of other famous voices, including Mariah Carey, Lin-Manuel Miranda and Chance the Rapper, who offered well-wishes and prayers for the the 76-year-old singer.
The 18-time Grammy victor is one of the best-selling artists of all time and was inducted into the Rock and Roll Hall of Fame in 1987. "I would call her the life blood".
The 18-time Grammy award victor maintained ties with the church throughout the years, including making financial contributions and hosting events. "Ask that God's richest blessings be bestowed upon her".
Clarence Waldron, Franklin's former publicist, said Wednesday he was grappling with the singer's health crisis.
In an unusual move, a tribute concert produced by Live Nation and spearheaded by Sony Music Chief Creative Officer Clive Davis, who signed Franklin to Arista Records in 1980, has already been announced. It's from 2015's Kennedy Center Honors, and it's the time that Franklin brought the house - including President Barack Obama - to tears.
That same year, Detroit named a street after her. One of those select events was a gala for Elton John's 25th anniversary of his AIDS foundation in November in New York City.