The two-minute spot, titled "Dream Crazy" depicts an inspirational montage of athletes overcoming adversity to chase their dreams that is sequenced with a narraration by Kaepernick.
At the end of the commercial, Kaepernick turns to the camera and says, "So don't ask if your dreams are insane". He is also seen juxtaposed against an image of the American flag in the ad, while reiterating the now controversial statement, "Believe in something".
Not surprisingly, Republicans polled were more likely to view the protests negatively, with 86 percent saying they found the protests unpatriotic, along with 57 percent of independents and 33 percent of Democrats.
But not everyone is in support of this new ad. People have been posting on social media of them cutting up their Nike gear and some even going as far as burning it.
The ad could ultimately alienate customers and turn them to rivals' products - which is not the objective of a marketing campaign, Saunders said.
Why Nike would do a deal with Kaepernick is "the million dollar question", she said. But the Kaepernick ad struck a nerve, timed just before the National Football League season kicks off on Thursday.
As a result, some wondered whether Trump tempered his response to Nike's Kaepernick ad simply because the company is paying rent to the Trump Organisation. "This means it could ultimately alienate and lose customers, which is not the objective of a marketing campaign".
Nike is, in fact, the Trump Organisation's biggest tenant in a single space, with the company leasing 65,000 square feet (just over 6,000 metres square) of space on East 57th Street for Niketown.
Moore said Nike could be hurt short-term in the court of public opinion, but does not expect the company's long-term sales to be affected very much.
Amin continued, "This is a huge positive move for a global brand, a Fortune 500 brand, to take a stand on a hot topic like this".
Even on the Labor Day holiday, Nike dominated social media. As numbers from YouGov's Plan & Track show, 34% of United States adults have a positive opinion of Kaepernick, while 31% have a negative one.
But Wesley Callaway, of Omaha, Nebraska, said he doesn't agree with kneeling during the national anthem and thinks it is unfortunate Nike is featuring Kaepernick, though he said he doesn't buy many Nike products and won't make any changes in his shopping habits.
"I think that what the university needs to do, is recognize that the money they get from Nike is now blood money, the blood money of the officers in Dallas who gave their lives while protecting protesters in a Black Lives Matter rally", said Brammer.