Incredibly, it's the EIGHTH hat-trick that Messi has scored in the Champions League.
Dembele lashed home Barcelona's second from long range in the 74th minute before Messi rounded off another dazzling display despite French defender Samuel Umtiti's late red card for two bookable offences.
Then, in the 77th minute, Messi found the back of the net once more to push Barcelona's lead to 3-0. "He is the best player in the world, [the best] in the history of the game". Cristiano Ronaldo has scored seven and plays for Juventus on Wednesday against Valencia. The Argentine is now ahead of the Portuguese in the feat and has now scored 48 hat-tricks in all competitions.
But even if Messi remains as good as ever, his team will need others to step up. Philippe Coutinho was impressive here and, after a hard debut campaign, Dembele is finding his rhythm, and his place.
"It's a blessing to have Messi in your side and a problem for anyone that doesn't [have him]", Barca coach Valverde said in his postgame news conference.
Last season, Messi added to Barcelona's 6-1 demolition of Girona by slotting a free kick under the defensive wall. "It is a thorn in our side", Luis Suarez said.
"Messi, like all of us, is really motivated to win big things [this season] and the Champions League is one of them".
What did you make of Messi's free-kick?
"We have to pinch ourselves to remind us that we are living through a unique era". Wastefully curled an effort off-target early in the second half before seeing PSV's goalkeeper claw out a better hit.
Zoet was beaten all ends up as Suarez dug out a marvellous lob from the edge of the area, only for the Uruguay worldwide to be cruelly denied by the bar. Messi's stunning 20-yard free kick broke the deadlock, whisked high over Zoet and into the top corner. First Dembele, after leaving two PSV midfielders for dead with a dragback, unleashed into the bottom corner.
Visiting manager Mark van Bommel had no complaints with the defeat, but did feel the final result slightly flattered Barca.